In an exploratory cross-disorder meta-analysis of the Genetic and Environmental Risk in Alzheimer’s Disease (GERAD) study for both obesity and AD, an IQ motif containing K gene (IQCK) was identified that showed the same direction of a risk allele for both AD and obesity (Hinney et al., 2014). The gene discussed is IQCK; the disease is obesity due to melanocortin 4 receptor deficiency.