The clinical relevance of CSTL1, FJX1, IER5L, and KLHL35 in 521 colon cancer cases was assessed, showing the expression level of CSTL1 mRNA was higher than that in normal tissues, and the expression levels of PD, SD, PR, and CR were higher than those in normal tissues (Supplementary Figure S1). Here, KLHL35 is linked to colonic neoplasm.