ROC analysis was applied to evaluate the effectiveness of FCNs mRNA expression levels in distinguishing hepatocellular carcinoma from normal liver tissue, and the AUC of FCN1 was 0.697 (95% CI: 0.628-0.767) (Figure 4A) obtained by analysis of TCGA-LIHC data. This evidence concerns the gene FCN1 and hepatocellular carcinoma.