In 2014, the American Diabetes Association (ADA), together with the National Kidney Foundation (NKF), recalled DN and CKD caused by diabetes with a constant assessment of glomerular filtration rate (GFR)<60 ml/min/1.73 m2 and/or urinary albumin/creatinine ratio (ACR) >30 mg/g for more than three months [1]. Here, ALB is linked to diabetes mellitus.