TPH2 and epilepsy: MRIstudies found brainstem atrophy from the medulla into the midbrain in SUDEPcases,8 activation of DRserotonergic neurons in an animal epilepsy model suppressed tonic seizures and respiratoryarrest,23 and DR activationreduced PGES length.24 We didnot detect changes related to serotonin signalling (TPH2 and SERT were not different,serotonin receptors were not detected).