DNER and head and neck squamous cell carcinoma: Given that BRD proteins are responsible for mediating gene transcription and are the main targets of BET inhibitors, we investigated the expression of this family of proteins both in our cell line panel and in the HNSCC TCGA data (Rathert et al., 2015; Kurimchak et al., 2016; Iniguez et al., 2018; Cheng et al., 2019; Cochran et al., 2019).