Similar results were reported by some authors who found that children with nephrotic syndrome had normal prothrombin time and no significant differences in PT values when compared between disease pairs such as remission and relapse [21, 29, 30] and onset and control [29] Although the authors offered no explanation for this finding, it is plausible to think that the coagulation factors involved in the extrinsic pathway i.e. Factors III and VII are not lost in urine. Here, F2 is linked to nephrotic syndrome.