ITGAV and pancreatic adenocarcinoma: For example, Cheuk et al. [8] showed high-ITGAV expression causing breast cancer metastasis; Kemper et al. [35] identified that ITGAV expression contributed to PAAD; Loeser et al. [6] revealed the relationship between ITGAV expression and unfavorable prognosis for patients with esophageal adenocarcinoma.