All participants were classified into four groups based on the presence or absence of MetS combined with the level of hs-CRP: MetS-CRP- group (n = 69,413), MetS-CRP + group (n = 14,576), MetS + CRP- group (n = 6,512), and MetS + CRP + group (n = 2,269). The gene discussed is CRP; the disease is metabolic syndrome.