Compared with the MetS-CRP- group, the MetS + CRP + (HR = 2.91; 95% CI 1.77–4.81; P < 0.001) and MetS-CRP + groups (HR = 1.36; 95% CI 1.05–1.75; P = 0.019) were associated with higher PLC risk, but the MetS + CRP- group had no significant association with an elevated risk of PLC (HR = 1.18; 95% CI 0.76–1.82; P = 0.390) (Table 3). The gene discussed is CRP; the disease is metabolic syndrome.