In sensitivity analyses for dementia subtypes, significant associations of low ALT (HR 0.987, 95% CI: 0.981–0.994, p = 0.006), urate (HR 0.998, 95% CI: 0.997–0.999, p = 0.004) concentrations with AD were described in Fig. 4 and Supplementary Table 7. The gene discussed is GPT; the disease is dementia.