High expression of ZNF655 was observed in 21 of 66 low-grade pancreatic cancer (WHO II; 13.13%) and in 22 of 31 high-grade pancreatic cancer (WHO III–IV; 70.97%) (Table 2), suggesting that increased ZNF655 expression was found in higher tumor grade. This evidence concerns the gene ZNF655 and familial pancreatic carcinoma.