STC1 and glioblastoma: To confirm the regulatory effects of circPOSTN/miR-219a-2-3p/STC1 axis in GBM progression, we conducted gene set enrichment analysis (GSEA) using TCGA dataset from GBM samples and found that elevated STC1 expression linked to the neovascularization and GBM cell proliferation phenotypes (Fig. 5G, all P < 0.05).