However, the proportions of IFN-γ+ in CD4+ (Th1) and IL-17+ in CD4+ (Th17) cells did not show significant differences between psoriasis patients and HC (Fig. 4d), as did the proportions and the numbers of CD45RO+ in CD3+CD4+ (CD4+ memory T), CD25+CD127−/low in CD3+CD4+ (Treg) and CCR7+CD45RA- in CD3+CD8+ (CD8+ TCM) cells (Fig. 4a–c). Here, CD4 is linked to psoriasis.