In a systematic review and meta-analysis, the DNI’s pooled sensitivity and specificity as a predictive factor for infection were 0.67 (95% CI, 0.62–0.71) and 0.94 (95% CI, 0.94–0.95), respectively, with an AUC of 0.89 [4]; these results were comparable to those of CRP [28] and procalcitonin [29] as predictive factors for infection in previous studies. Here, CRP is linked to infection.