However, there was no significant diagnostic capability to distinguish COVID-19 positive from healthy cohort from the overall analysis of relative abundance of GPs or subclass traits (AUC for ROC analysis < 0.80, P > 0.005, as shown in Fig. 4 and Supplementary Information ST IV) except for GP27(%), GP42(%), and S4(%), which individually showed excellent diagnostic performance accuracy (AUC for ROC analysis > 0.80, P < 0.005, (Fig. 4 and Supplementary Information ST IV). Here, CD151 is linked to COVID-19.