IL17A and psoriasis: Interestingly, IL-17 targeted therapy affected to a various extent the percentages of these T-cell populations, but intracellular IL-17 production also differed between these cell subsets in psoriasis patients as shown in Supplementary Fig. S6, further indicating that the immunophenotypic characteristics of those cells and their ability to be affected by treatment-induced IL-17 inhibition is diverse and must be characterized further at the functional level.