Therefore, in this study we investigated role of dynamin-2, clathrin and caveolin-1 in HAdV26 infection in A549 cell line, which is commonly used for adenovirus research, and previously constructed clone A549-E6 with stably increased expression of αvβ3 integrin that allows better infection with HAdV26 compared to parental A549 cells (11). This evidence concerns the gene DNM2 and infection.