CAV1 and infection: We have shown here that HAdV26 infection of A549 cells which have very low amount of αvβ3 integrin involves dynamin-2 and is caveolin-1-independent, while infection of A549-E6 cells which express high amount of αvβ3 integrin involves dynamin-2- and is caveolin-1-dependent, indicating that caveolin-1 is limiting factor in αvβ3 integrin-mediated HAdV26 infection.