Actin‐binding protein Anillin is a key regulator of the cell cycle, and in our previous research, Actin‐binding protein Anillin is a key regulator of the cell cycle, and in our previous research, it has been verified as targeted by the transcription factor sex‐determining region Y‐related (SRY)‐Box Transcription Factor 4 (SOX4) in transcription and playing a potent promoting effect on the process of cytokinesis and tumor growth in HCC.12 The gene discussed is SOX4; the disease is hepatocellular carcinoma.