AKT1 and neoplasm: To define the nature of tumour‐associated F4/80‐positive cells in these models, we looked at co‐expression of F4/80 with macrophage polarization markers CD163 (a classical pro‐inflammatory marker) and CD68 (a classical pro‐restorative marker) in our Nicd/Akt‐driven model with and without the overexpression of DKK1.