On the other hand, because of the high prevalence of ALDH2*2 allele among East Asian populations, East Asians may be more susceptible to the carcinogenic effect of alcohol, with most evidence coming from studies of esophageal cancer and head and neck cancer (32), however, perhaps, a more comprehensive study assessing the influence of alcohol intake on the postoperative TFOM reconstructive surgery complications in both Asian and non-Asian populations would be needed in the future. This evidence concerns the gene ALDH2 and head and neck cancer.