This meta-analysis aimed to investigate the predictive value of pretreatment LDH and dNLR for NSCLC progression in patients treated with PD-1/PD-L1 inhibitors.<h4>Methods</h4>PubMed, Embase, and the Cochrane Library were searched by two researchers independently for related literature before March 2020. This evidence concerns the gene CD274 and non-small cell lung carcinoma.