Patients can be on DAPT (low-dose aspirin plus a P2Y12 inhibitor, either clopidogrel or prasugrel or ticagrelor) according to current guidelines136,139 for the following indications: acute minor ischemic stroke or high-risk TIA within the first 21 days; prior TIA/stroke with intracranial arterial culprit lesion within 90 days; percutaneous coronary intervention (PCI) and stent implantation for stable CAD within 6 months; ACS with or without revascularization within 12 months. The gene discussed is P2RY12; the disease is transient ischemic attack.