The transcription factor NF-κB is associated with a number of inflammatory signals, and the genes regulated by NF-κB play important roles in maintaining many aspects of cellular activity, such as immune responses to viral/bacterial infection, cell proliferation-survival-apoptosis, stress, and injury (Brockman et al., 1995; Sun, 2017). The gene discussed is NFKB1; the disease is bacterial infectious disease.