On the other hand, the effects of magnesium lithospermate B on attenuating renal function, renal fibrosis, and inflammation were investigated in 5/6Nx rats, showing a reduction in the expressions of FN, Col III, Col IV, TNF-α, and monocyte chemoattractant protein-1 (MCP-1), which are associated with inhibition of TF activation (Wang et al., 2019). This evidence concerns the gene CCL2 and renal fibrosis.