The 10 prognostic risk genes identified in our study included ABCB6, ANKZF1, CENPA, DLAT, G6PD, GOT2, HOMER1, ME1, PHKA2, and STC2. Among these genes, the ABCB6 expression was upregulated in HCC, and its high expression was correlated with poor prognosis (Polireddy et al., 2011). This evidence concerns the gene ANKZF1 and hepatocellular carcinoma.