AHSG and sarcomatoid carcinoma: Kundranda et al. (2005) found that fetuin-A promotes the tumorigenesis of Lewis lung carcinoma via adhesive-dependent and adhesive-independent pathways. In addition, bovine fetuin-A was demonstrated to bind to the plasma membrane of squamous and spindle cell carcinoma cells (Leite-Browning et al., 2002). Consistently, another study suggests that fetuin-A contributes to the early stages of skin tumorigenesis (Leite-Browning et al., 2004).