The serum levels of IL-8 (p = 0.003) and SAA (p = 0.01) in the anxiety group were significantly lower than those in the non-anxiety group, while other markers of inflammation, including TNF-α, IL-1β, IL-2R, IL-6, IL-10, hs-CRP, CRP, and ESR did not demonstrate significant differences between the two groups. The gene discussed is TNF; the disease is Anxiety.