It has been summarized that pharmacological inhibitors targeting IKKβ (a major downstream effector of the NF‐κB pathway), such as PS‐1145, SAR113945, IKK‐16, BAY11‐7082, BAY11‐7085, SC‐514, TBK‐1, BoNT, vincristine, and resveratrol, can be potential strategies against severe COVID‐19.282. This evidence concerns the gene NFKB1 and COVID-19.