According to the GSEA KEGG analysis, SRR co-expressed genes were involved in oxidative phosphorylation, peroxisome, Parkinson’s disease, alpha-linolenic acid metabolism, fatty acid degradation, fructose and mannose metabolism, p53 signaling pathway, butanoate metabolism, Alzheimer’s disease, fatty acid metabolism, and ferroptosis. The gene discussed is TP53; the disease is early-onset autosomal dominant Alzheimer disease.