We mapped the eQTLs of ACE2 that existed in the ACE2 promoter in EUR and CHB populations and verified the possible regulatory function of one candidate SNP rs2106809, which is a brain eQTL of ACE2. In our detailed examination of the COVID-19 hospitalization GWAS of the EUR ancestry from the UK Biobank (Figure 1C), we revealed the minor allele G of rs2106809 is protective against COVID-19 hospitalization, although its association was only nominally significant (p = 0.047). The gene discussed is ACE2; the disease is COVID-19.