In addition, restricting the analysis to participants who never drank alcohol (adjusted for age, sex, BMI, SBP, DBP, ALT, AST, sCr, smoking status, and family history of diabetes), the results suggested that the HR between the TG/HDL-c ratio and the risk of diabetes in prediabetic patients was 1.115 (95% CI : 1.059–1.175, P < 0.001). This evidence concerns the gene GPT and diabetes mellitus.