Alternative splicing isoforms of vascular endothelial growth factor A (VEGFA), UDP glucuronosyltransferase family 1 member A complex locus (UGT1A), pregnane X receptor (PXR), and KRAS are potential therapeutic targets for CRC (Audet-Delage et al., 2017; Canavese et al., 2017; Eilertsen et al., 2019). The gene discussed is NR1I2; the disease is colorectal carcinoma.