Higher levels of tau (453.6 ± 343.5 pg/mL) and tau phosphorylated at T181 residue (67.8 ± 18.0 pg/mL) were detected in cerebrospinal fluid (CSF) of AD patients (Haense et al., 2008; Kandimalla et al., 2013). The gene discussed is MAPT; the disease is Alzheimer disease.