FUT2 and infection: Unlike the susceptibility to IBD, HBGA expression under the influence of the FUT2 gene is an important susceptibility risk for NoV infection, and secretor status is associated with susceptibility to NoV infection (Currier et al., 2015; Haga et al., 2020), while non-secretors lack enzyme coded by FUT2 resulting in high resistance to infection and gastroenteritis caused by numerous NoV strains.