One of the known ligands of integrin αvβ1 is fibronectin (Koths et al., 1993), which is a key glycoprotein in the cancer‐related extracellular matrix (Zhang et al., 1993) and can bind to integrins via the RGD motif recognition to mediate cell adhesion (Saad et al., 2002). The gene discussed is FN1; the disease is cancer.