CXCL8 and malignant colon neoplasm: In addition, the area under the curve (AUC) value for CXCL8 was 0.7212 (95% confidence interval: 0.6777 to 0.7647, p < 0.0001) (Fig. 2I), which means that CXCL8 could be regarded as a better prognostic biomarker for colon cancer patients.