ABCG2 and gout: ABCG2 rs372192400 (R147W), rs753759474 (T153M), rs752626614 (F373C) and rs200894058 (S572R) could down-regulate the expression of ABCG2 [68]. ABCG2 rs2054576 is related to HUA in the Korean population [70]; rs72552713 is associated with gout susceptibility in Vietnamese population [48]; c.725 T > C (p. I242T) is involved in the occurrence of early-onset HUA and gout [71].