PPIB and obesity due to melanocortin 4 receptor deficiency: Thus, there are still some problems that need to be further explored on how to maintain its stability in the solution, such as investigating the selection of stability indicators, the mutual interference of the ingredients in the compound, the influence of excipients on stability and the reaction mechanism, etc. Obesity-related OA is a complex regulatory network, and what role Sal B plays in this regulatory network still needs to be explored before the clinical application of Sal B in the treatment of obesity-related OA.