As shown in Table 3, according to the obtained regression model, expression of PPARγ protein expression in tumor site can be effective in predicting malignancy of bone tumors (OR = 1.59, CI = 1.28–1.98, P-value < 0.0001); the OR was not statically significant for PPARγ gene expression and tumor malignancy. This evidence concerns the gene PPARG and bone neoplasm.