Moreover, osteosarcoma patients suffering from metastasis (0.36 ± 0.18) expressed higher level of PPARγ mRNA level compared to non-metastatic patients (0.19 ± 0.1) (P = 0.0051); while the difference between Ewing Sarcoma metastatic and non-metastatic tumors was not significant (Fig. 2b). Here, PPARG is linked to osteosarcoma.