Data regarding the relevance of PPARγ to the Ewing Sarcoma is limited and most of the results have been obtained from studies on osteosarcoma cancer cells; however, the expression pattern of PPARγ in these tumors has not been studied and most of the evidence is from the stimulation of PPARγ with various agonists and the effect on the death and proliferation of osteosarcoma cells [27]. The gene discussed is PPARG; the disease is Ewing sarcoma.