Many immune checkpoint molecules, including Programmed Death 1 (PD-1) and its ligands PD-L1 and PD-L2; Cytotoxic T Lymphocyte Activator 4 (CTLA-4); Lymphocyte Activation Gene 3 (LAG-3), and CD200, among others, involve in tumor immunology [7]. Here, LAG3 is linked to neoplasm.