In general, high levels of MALAT1 expression have been demonstrated in the vast majority of CRC specimens compared to adjacent non-tumor control colorectal tissue specimens in cancer patients (Sun et al. 2019b; Zheng et al. 2020; Luan et al. 2020; Xiong et al. 2018; Li et al. 2017a). This evidence concerns the gene MALAT1 and neoplasm.