Potentially both miR-140-5p and miR-140-3p could be sponged by lncRNA MALAT1, although this has not been shown in CRC, while the direct interaction of miR-140-5p with MALAT1 has been shown experimentally in cancers of various types such, as prostate cancer (Hao et al. 2020), hepatocellular carcinoma (Fan et al. 2020; Hou et al. 2020), osteosarcoma (Sun and Qin 2018), tongue squamous cell carcinoma (Zhu et al. 2019). Here, MALAT1 is linked to osteosarcoma.