In addition, this capacity of MC-C tumor lysate was correlated to its high concentration of HGMB1 and Hsp60 – two recognized danger signals that favor DC maturation – and low concentration of IL-10 and TGF-β – two known immunosuppressive cytokines that inhibit DC maturation [1, 24]; (Fig. 1E and F). Here, TGFB1 is linked to neoplasm.