Polyadenylated RNA was isolated from the U87 glioblastoma cell line, which has low ADAR3 expression24, and U87 cells transduced with a virus expressing ADAR3 under the control of the CMV promoter, which we have shown previously to provide a high ADAR3 expressing glioblastoma cell line condition24. Here, ADARB2 is linked to glioblastoma.