YAP1 and focal segmental glomerulosclerosis: Previously, several studies showed that loss of YAP in podocytes causes a glomerular disease (FSGS) phenotype (Schwartzman et al, 2016), that YAP activation has a protective effect during injury (Meliambro et al, 2017), and that nuclear localisation/activation of YAP has a pro-survival effect in podocytes (Bonse et al, 2018).