Mutations in numerous RP coding genes, other than human RPS21e, are associated with the blood disorder Diamond-Blackfan anemia (DBA) (Narla and Ebert 2010; Horos et al. 2012; Mills and Green 2017; Khajuria et al. 2018; Aspesi and Ellis 2019; Costa et al. 2020). This evidence concerns the gene BLOC1S3 and hematologic disorder.