Although ALT is the TMM commonly utilized by osteosarcomas, many of these tumors have wt ATRX, a gene which is frequently mutated in ALT‐positive cancers (Ulaner et al, 2003; Sanders et al, 2004; Henson et al, 2005; Chen et al, 2014; Liau et al, 2015). This evidence concerns the gene ATRX and osteosarcoma.