The adjusted risks of death being higher among PLWH with low CD4 count (<500 cells/μL), supports the hypothesis that the excess risks of these outcomes were unlikely directly HF-related given that low CD4 count was not independently associated with a higher risk of HF hospitalizations or HF-related ED visits, and PLWH having low CD4 count are known to be at higher risk for premature death due to non-cardiovascular causes.35 The gene discussed is CD4; the disease is hydrops fetalis.