After accounting for variation in baseline characteristics including sociodemographic features, comorbidity burden, and receipt of guideline-directed medical therapies for HF, there were no differences in adjusted risks of all-cause death, HF hospitalization, or HF-related ED visits among PLWH with baseline CD4 counts of ≥500 cells/μL when compared with persons without HIV. Here, CD4 is linked to hydrops fetalis.