CASP9 and cancer: 6-GIN‐induced apoptosis of cancer cells was associated with proteins such as BCL‐2, survivin, Bax, caspase‐3 and caspase-9, and MAPK. Intracellular ROS levels regulate the 6-GIN‐induced cell death and TG100-115 or tranilast had an effect of enhancing the 6-GIN‐induced cell death.