TGFB1 and periodontal disorder: Serum levels of TGF-β and TGF-β mRNA in tissue can be measured and used as diagnostic or prognostic markers for human disease.4 The present study aimed to determine the association of periodontal disease with the Th17/Treg balance by examining the genetic expression of IL-17 and TGF-β, which influence the incidence and suppression of inflammation.