SOD1 and hepatocellular carcinoma: In summary, TKPP can effectively promote the antioxidant effect of human hepatoma cell line HepG2 and human umbilical artery smooth muscle cells HUASMC and resist oxidative damage and apoptosis induced by H2O2 by enhancing the expressions of GSH, CAT, and SOD in the natural antioxidant system and the level of NO secretion.